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采用体外培养、动物接种方法研究了杂色曲霉素对体外培养的人胚支气管粘膜上皮致癌作用。结果发现，体外培养的人胚肺支气管组织块在杂色曲霉素处理后，γ射线照射的新生ＳＤ仔鼠皮下接种可见支气管粘膜及肺泡上皮增生，并可见支气管粘膜上皮的异形增生灶
The in vitro culture and animal inoculation methods were used to study the carcinogenic effects of ochratoxin on cultured human embryonic bronchial epithelium. The results showed that after in vitro culture of human embryonic lung bronchial tissue blocks treated with ochratoxin, bronchitis and alveolar epithelial hyperplasia were observed by subcutaneous inoculation of neonatal SD rat neonates irradiated with gamma rays, and epithelial dysplasia of bronchial mucosa epithelium was observed.