毒素性休克综合征(TSS)首先由To-dd于1978年描述,是由金黄色葡萄球菌产生的一种新毒素引起。临床特点有高热、头痛、谵妄、结合膜充血、猩红热样皮疹、皮下水肿、呕吐、水泻、肝肾功能障碍、弥漫性血管内凝血、低血压或休克。恢复期面部、躯干、肢端有微细脱皮,血培养阴性。在Todd报告前已有人描述过因金黄色葡萄球菌各种局部感染而引起类似的临床表现。1980年Schrock首次提出TSS常 Toxin shock syndrome (TSS), first described by To-dd in 1978, is caused by a new toxin produced by Staphylococcus aureus. Clinical features include fever, headache, delirium, conjunctival congestion, scarlet fever-like rash, subcutaneous edema, vomiting, watery diarrhea, liver and kidney dysfunction, diffuse intravascular coagulation, hypotension or shock. Recovery period facial, trunk, extremities have fine peeling, blood culture negative. It was previously reported by Todd that similar clinical manifestations were caused by various local infections with S. aureus. Schrock first proposed TSS in 1980