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目的研究神香草Hyssopus cuspidatus Boriss.的化学成分。方法采用硅胶、Sephadex LH-20柱分离纯化,通过理化常数和光谱数据鉴定化合物的结构。结果从神香草乙醇提取物的乙酸乙酯和正丁醇部分分离得到7个化合物,经理化常数和波谱数据分析,分别鉴定为白杨素(Ⅰ)、二十四亚甲基环阿尔廷醇(Ⅱ)、齐墩果酸(Ⅲ)、正十六烷醇(Ⅳ)、蜡醇(Ⅴ)、β-谷甾醇(Ⅵ)、胡萝卜苷(Ⅶ)。结论化合物Ⅰ,Ⅱ,Ⅳ为首次从该植物中分离得到。
Objective To study the chemical constituents of Hyssopus cuspidatus Boriss. Methods The compounds were isolated and purified by silica gel and Sephadex LH-20 column. The structures of compounds were identified by physicochemical constants and spectral data. Results Seven compounds were isolated from the ethyl acetate and n-butanol fractions of ethanol extract of Herba Artemisiae, and were identified as chrysin (Ⅰ), tetramethylenetetracycline ), Oleanolic acid (Ⅲ), n-hexadecanol (Ⅳ), wax alcohol (Ⅴ), β-sitosterol (Ⅵ) and daucosterol (Ⅶ). Conclusion Compounds Ⅰ, Ⅱ and Ⅳ were isolated from this plant for the first time.