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本文对30例口服肠溶阿斯匹林冠心病患者检测了出血时间(BT),血小板集聚性(pAg)和水杨酸血浓度。在顿服阿斯匹林0.3克后2小时,BT由1.5分延长至3分,口服阿斯匹林0.3克/日者服药后七天,pAg明显受抑,达66%左右。隔日服阿斯匹林0.3克者,对pAg似无影响,服用肠溶阿斯匹林者未发现胃肠道不适和出血。口服潘生了0.15克/日能延长血小板寿命。作者认为,冠心病患者口服阿斯匹林0.3克/日和潘生丁0.15克/日较为适宜。
In this paper, 30 patients with oral enteric-coated aspirin coronary heart disease were detected bleeding time (BT), platelet aggregation (pAg) and salicylic acid concentration. Two hours after taking 0.3 g of aspirin, BT was extended from 1.5 to 3 minutes. Serum of pAg was significantly inhibited at about 66% after oral administration of aspirin 0.3 g / d for seven days. 0.3 grams of aspirin taken the next day, no effect on pAg, aspirin taking gastrointestinal patients found no gastrointestinal discomfort and bleeding. Oral Pan born 0.15 grams / day can extend platelet life expectancy. The authors believe that patients with coronary heart disease aspirin 0.3 g / day and dipyridamole 0.15 g / day is more appropriate.