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目的:分析鼻内镜辅助下开放径路联合放疗治疗中晚期上颌窦恶性肿瘤患者的临床疗效,并探讨进一步提高疗效的方法。方法:回顾性分析29例鼻内镜辅助下开放径路联合放疗治疗中晚期上颌窦恶性肿瘤患者的生存情况。结果:29例患者癌肿病灶均顺利切除,其中7例Ⅳ期行术前放疗加手术加术后放疗,22例采用手术加术后放疗。中位随访时间60个月(23~129个月)。全组患者3年和5年存活率分别为72%、61%,其中Ⅱ期分别为90%、80%,Ⅲ+Ⅳ期分别为63%、51%。结论:鼻内镜辅助下开放径路联合放疗是治疗上颌窦恶性肿瘤的一种有效的综合治疗方法,无远处转移Ⅳ期患者联合术前放疗仍可获得很好疗效。
Objective: To analyze the clinical effect of nasal endoscopy-assisted open-path combined with radiotherapy in the treatment of patients with advanced maxillary sinus cancer and explore ways to further improve the curative effect. Methods: A retrospective analysis of 29 cases of nasal endoscopic assisted open-path combined with radiotherapy for the treatment of advanced malignant maxillofacial malignant tumors in patients with survival. Results: Twenty-nine patients had successful resection of cancer lesions. Seven of them underwent preoperative radiotherapy combined with operation and postoperative radiotherapy, and 22 patients underwent surgery combined with postoperative radiotherapy. The median follow-up time was 60 months (range, 23 to 129 months). The 3-year and 5-year survival rates of all the patients were 72% and 61%, respectively, of which stage II were 90% and 80%, respectively, and stages III and IV were 63% and 51% respectively. Conclusion: Nasal endoscopy-assisted open-path combined radiotherapy is an effective and comprehensive treatment for maxillary sinus malignant tumors. There is still a good curative effect in patients with stage Ⅳ metastasis without preoperative radiotherapy.