最近用于控制严重预痫的药物在降血压方面不一定有效,且可能引起母儿严重副作用。心痛定(N)是一种钙通道阻滞剂,广泛用于与妊娠无关的高血压危象,理论上是治疗严重预痫的理想药物。为对其治疗严重预痫的效果和安全性作出评价,与有明显降压效果的肼苯哒嗪(H)进行了随机对照研究。 Recently, drugs used to control severe pre-eclampsia may not be effective in lowering blood pressure and may cause serious side effects in mother and child. Nocturnal Determination (N) is a calcium channel blocker, widely used in pregnancy-related hypertensive crisis, in theory, the ideal drug for the treatment of severe pre-eclampsia. To evaluate its efficacy and safety in the treatment of severe preeclampsia, a randomized controlled trial was conducted with hydralazine (H), which showed significant antihypertensive effect.