经典的直流极谱,因灵敏度的限制,在药物体内过程研究中,一直未能发挥重要作用。近十年来,由于脉冲极谱理论研究的进展,以及有关仪器的试制成功,极谱分析的检测下限已可达到ng 级。脉冲极谱仍保留直流极谱的许多优点,例如适用药物种类较多,检测浓度的线 Classical DC polarography, due to the limitations of sensitivity, has not been able to play an important role in the study of drug in vivo processes. In recent ten years, due to the progress made in the research of pulsed polarographic theory and the successful trial of related instruments, the detection limit of polarographic analysis can reach ng level. Pulse polarography still retains many advantages of DC polarography, such as more types of drugs available, the concentration of the line