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目的 :研究周围型肺癌MRI征象与nm23表达间的关系。材料和方法 :SABC检测45例周围型肺癌nm23表达水平 ,并研究与其术前MRI征象之间的关系。结果 :nm23表达与深分叶征及纵隔淋巴结转移有关(P<0 05) ,与组织学类型、分化程度、分期及瘤体直径、胸膜凹陷征、毛刺征、信号特点无关。结论 :nm23与肺癌转移有关 ,检测nm23的表达水平可反映肺癌的某些生物学行为。
Objective: To study the relationship between MRI signs and the expression of nm23 in peripheral lung cancer. MATERIALS AND METHODS: The expression of nm23 in 45 cases of peripheral lung cancer was detected by SABC and the relationship between the expression of nm23 and the preoperative MRI signs was analyzed. Results: The expression of nm23 was correlated with deep lobular sign and mediastinal lymph node metastasis (P <0.05), but not with histological type, differentiation degree, stage and tumor diameter, pleural indentation, burr sign and signal characteristics. Conclusion: nm23 is associated with lung cancer metastasis. The detection of nm23 expression may reflect some biological behaviors of lung cancer.