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目的分析并评价联合使用米非司酮与甲氨喋呤与单独口服米非司酮对异位妊娠患者的临床治疗效果。方法对我院自2009年11月至2010年12月期间收治的102例未破裂型异位妊娠患者,采用米非司酮联合甲氨喋呤对输卵管妊娠实施治疗。结果联合用药的治疗组有效率高于对照组,两组比较差异有统计学意义(P<0.01);两组患者在治疗前血β-HCG数值差异无统计学意义(P>0.05),治疗后两组血β-HCG回落至正常范围所需时间差异显著(P<0.05);两组平均住院时间差异显著(P<0.01),具有统计学意义。结论联合使用米非司酮与甲氨喋呤治疗异位妊娠临床疗效较理想,治疗后不良反应少,推荐临床上广泛推广应用。
Objective To analyze and evaluate the clinical effect of mifepristone combined with methotrexate and mifepristone alone on patients with ectopic pregnancy. Methods A total of 102 patients with unruptured ectopic pregnancy treated in our hospital from November 2009 to December 2010 were treated with mifepristone and methotrexate for tubal pregnancy. Results The effective rate of combined treatment group was higher than that of control group, the difference between the two groups was statistically significant (P <0.01); There was no significant difference between the two groups before treatment (P> 0.05) The time required for the return of β-HCG in the latter two groups to the normal range was significantly different (P <0.05). The mean length of stay in both groups was significantly different (P <0.01), with statistical significance. Conclusion The combination of mifepristone and methotrexate in the treatment of ectopic pregnancy clinical efficacy is ideal, less adverse reactions after treatment, it is recommended widely widely used in clinical practice.