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目的和方法 :用两株具有鼻咽癌相关抗原内影像的抗独特型单克隆抗体 2Ｈ4、5Ｄ3,经氢氧化铝凝胶沉淀法制备成抗独特型疫苗Ａｌｕｍ - 2Ｈ4、Ａｌｕｍ - 5Ｄ3,对 1 9例晚期鼻咽癌放疗病人作主动免疫治疗 ,9例放疗加生理盐水注射为对照组。用ＥＬＩＳＡ检测治疗前后病人血清抗体
OBJECTIVE AND METHODS: Anti - idiotypic vaccine Alum - 2H4, Alum - 5D3 were prepared by aluminum hydroxide gel precipitation with two anti - idiotype monoclonal antibodies 2H4 and 5D3 with internal images of nasopharyngeal carcinoma related antigen. 9 cases of patients with advanced nasopharyngeal carcinoma radiation therapy for active immunotherapy, 9 cases of radiotherapy and saline injection as the control group. Serum antibodies were measured by ELISA before and after treatment