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目的观察甘露聚糖肽联合顺铂腔内灌注治疗腺癌性胸腹水的疗效。方法将37例腺癌性胸腹腔积液患者随机分为两组,治疗组应用甘露聚糖肽联合顺铂胸腔注入,对照组顺铂单药治疗。结果两组有效率无统计学差异;治疗组骨髓抑制发生率低于对照组。结论甘露聚糖肽联合顺铂治疗腺癌性胸腹腔积液与顺铂单药治疗,疗效无明显差异,但能减轻骨髓抑制。
Objective To observe the curative effect of intraperitoneal perfusion of mannan and cisplatin on adenocarcinoma pleural effusion. Methods Thirty-seven patients with ascites and pleural effusion were randomly divided into two groups. The treatment group was treated with mannan plus cisplatin and the control group with cisplatin alone. Results There was no significant difference between the two groups; the incidence of bone marrow suppression in the treatment group was lower than that in the control group. Conclusion Mannatide combined with cisplatin treatment of adenocarcinoma of pleural effusion and cisplatin monotherapy, no significant difference in efficacy, but can reduce bone marrow suppression.