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满城某村运动鞋厂,自1990年12月至1991年3月相继发现部分患者感到乏力、头晕,心悸。并牙龈出血,皮下瘀斑。经流行病学调查、临床资料、血象、骨髓象分析,诊断为再生障碍性贫血。现报告如下。发病情况:该厂绷楦车间共24人,发病18例,发病率75%,男性6例,女性12例。临床特点:乏力、头晕、心悸、牙龈出血,皮下瘀斑,皮肤粘膜、甲床苍白为主,女性病员并有月经提前、量多等症状。实验室检查:血象全血细胞减少,骨髓象为骨髓增生减低或极度减低,白细胞碱性磷酸酶各积分均>200分。
Mancheng village sports shoes factory, from December 1990 to March 1991 have been found in some patients feel fatigue, dizziness, palpitations. And bleeding gums, ecchymosis. The epidemiological survey, clinical data, blood, bone marrow analysis, diagnosis of aplastic anemia. The report is as follows. The incidence of the situation: the plant a total of 24 people last plant, the incidence of 18 cases, the incidence rate of 75%, 6 males and 12 females. Clinical features: fatigue, dizziness, palpitations, bleeding gums, subcutaneous ecchymosis, skin and mucous membranes, a pale bed, female patients and have early menstruation, volume and other symptoms. Laboratory tests: blood pancytopenia, myeloid bone marrow hyperplasia as reduced or greatly reduced, leukocyte alkaline phosphatase each score was> 200 points.