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目的:探讨化疗后前纵隔胸腺部位FDG摄取增高的意义。方法:回顾分析49例化疗后行FDGPET检查的肿瘤患者胸腺部位FDG摄取灶的变化情况。男性19例,女性30例;年龄5～71岁,平均27.3岁。其中26例患者之后进行PET随访,17例行CT随访,6例行PET和CT随访。平均随访时间11.3个月。结果:49例患者随访结果显示,48例PET图像上胸腺部位FDG摄取无明显增强和(或)CT图像上显示局部软组织缩小。1例患者为原发性胸腺癌患者。结论:肿瘤患者化疗后纵隔部位的三角形轻至中度FDG摄取,可能与短暂性的胸腺良性增生反应有关,不代表恶性病变。
Objective: To investigate the significance of increased FDG uptake in anterior mediastinal thymus after chemotherapy. Methods: The changes of FDG uptake in the thymus of 49 cancer patients undergoing FDG PETET were retrospectively analyzed. 19 males and 30 females; aged 5 to 71 years, mean 27.3 years old. Twenty-six of the patients were followed up with PET, 17 with CT followed up, and 6 with PET and CT follow-up. The average follow-up time was 11.3 months. Results: The follow-up results of 49 patients showed no significant increase in uptake of FDG in the thymus of 48 cases of PET images and / or reduction of local soft tissue on the CT images. One patient had primary thymoma. CONCLUSION: Triangular mild to moderate FDG uptake in the mediastinum of cancer patients after chemotherapy may be related to transient thymus hyperplasia, not to malignant lesions.