苯巴比妥于1911年合成,为一优良催眠剂,惟不溶于水。其后制成水溶性的鈉鹽,广用为安瓿剂的原料。但因其水溶液不稳定,放置过久,徐行分解,致使含量降低,故一般制成粉剂安瓿供用。苯巴比妥鈉的定量方法,文献上記載颇多,但有些方法不是操作煩复,便是限于目前設备条件,未能广泛应用,如非水溶液滴定法,电位滴定法,極譜分析法等。現將各种定量方法举列于下。 Phenobarbital was synthesized in 1911 as an excellent hypnotic agent but insoluble in water. Then made of water-soluble sodium salt, widely used as raw material for ampoules. But because of its unstable aqueous solution, placed too long, Xu line decomposition, resulting in reduced content, it is generally made of powder ampoules for use. Quantitative method of phenobarbital sodium, the literature records a lot, but some methods are not operating troublesome, is limited to the current equipment conditions, not widely used, such as non-aqueous titration, potentiometric titration, polarography Wait. Now a variety of quantitative methods are listed below.