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目的 研究碱性成纤维细胞生长因子（bFGF）对新生儿缺氧缺血性脑病（HIE）的治疗作用。方法随机分成治疗组和对照组。对照组常规处理,治疗组在常规处理基础上肌注bFGF4000U,观察临床表现和头颅CT恢复情况。结果 治疗组总有效率95.65％,对照组总有效率71、11％。治疗组总有效率明显高于对照组,差异非常显著（P<0.001）。结论bFGF对HIE患儿有明显的治疗作用。
Objective To investigate the therapeutic effect of basic fibroblast growth factor (bFGF) on neonatal hypoxic-ischemic encephalopathy (HIE). Methods were randomly divided into treatment group and control group. Control group routine treatment, the treatment group on the basis of conventional treatment intramuscular bFGF4000U, observed the clinical manifestations and cranial CT recovery. Results The total effective rate was 95.65% in the treatment group and 71,11% in the control group. The total effective rate of the treatment group was significantly higher than that of the control group, the difference was significant (P <0.001). Conclusion bFGF has a significant therapeutic effect on children with HIE.