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目的探讨三维适形调强放疗在宫颈癌根治性放疗中的应用效果。方法选取邢台市人民医院2010-01-2011-01收治的52例宫颈癌患者,根据放射治疗技术将其随机分为研究组与对照组,研究组采用三维适形调强放疗技术,对照组采用传统放疗技术,比较两组患者的放疗效果。结果研究组治疗有效率为92.30%,对照组治疗有效率为76.92%。研究组1年生存率为92.30%,3年生存率为76.92%,5年生存率为61.53%;对照组1年生存率为76.92%,3年生存率为69.23%,5年生存率为53.84%。研究组皮肤反应2例,放射性直肠炎1例,放射性膀胱炎2例,不良反应发生率19.23%,对照组皮肤反应4例,放射性直肠炎3例,放射性膀胱炎3例,骨髓抑制2例,不良反应发生率为46.15%。两组治疗有效率、生存率和并发症发生率差异有统计学意义,P<0.05。结论宫颈癌根治性放疗采用三维适形调强放疗的临床效果更好,有效提高患者放疗后不同阶段生存率,值得临床借鉴应用。
Objective To investigate the application of three-dimensional conformal IMRT in radical radiotherapy of cervical cancer. Methods 52 cases of cervical cancer admitted to Xingtai People’s Hospital from January 2010 to January 2011 were selected and randomly divided into study group and control group according to the radiotherapy technique. The study group adopted three-dimensional conformal IMRT radiotherapy and the control group Traditional radiotherapy techniques compared radiotherapy effects in both groups. Results The study group’s effective rate was 92.30%, while the control group’s effective rate was 76.92%. The 1-year survival rate of the study group was 92.3%, the 3-year survival rate was 76.92%, and the 5-year survival rate was 61.53%. The 1-year survival rate was 76.92% in the control group, 69.23% in 3-year survival rate and 53.84 in 5-year survival rate %. There were 2 cases of skin reaction, 1 case of radiation proctitis, 2 cases of radiation cystitis, 19.23% of adverse reactions, 4 cases of skin reaction in control group, 3 cases of radiation proctitis, 3 cases of radiation cystitis, 2 cases of bone marrow suppression, The incidence of adverse reactions was 46.15%. The two groups of treatment efficiency, survival and complication rates were significantly different, P <0.05. Conclusion The clinical effect of three-dimensional conformal IMRT on radical radiotherapy for cervical cancer is better and the survival rate of patients in different stages after radiotherapy is effectively improved, which is worthy of clinical reference.