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给Ｗｉｓｔａｒ大鼠喂养ＤＡＢ饲料诱发肝癌，同时饮用１０％中华麦饭石浸液共２６ｗｋ。在实验第８、１８和２６ｗｋ，用脾细胞增殖法和间接免疫荧光法检测白细胞介素－２（ＩＬ－２）活性和Ｔ淋巴细胞亚群。结果显示：实验组ＩＬ－２活性和辅助Ｔ细胞（ＴＨ）／抑制Ｔ细胞（Ｔｓ）比值３次均显著高于对照组（Ｐ＜０．０５～０．００１）。在第１８和２６ｗｋ，实验组总Ｔ细胞（ＴＧ）和ＴＨ细胞显著高于对照组（Ｐ＜０．０５～０．０１），Ｔｓ细胞显著低于对照组（Ｐ＜０．０５～０．０１）。结果表明：中华麦饭石能显著升高肝癌大鼠ＩＬ－２活性，阻止Ｔ淋巴细胞亚群改变。其作用机制可能与中华麦饭石富含的微量元素有关。
Wistar rats were fed with DAB feed to induce liver cancer, while drinking 10% Chinese medical stone immersion liquid for 26 weeks. Interleukin-2 (IL-2) activity and T-lymphocyte subsets were measured using splenocyte proliferation assay and indirect immunofluorescence assays at 8, 18, and 26 weeks. The results showed that the activity of IL-2 and the ratio of helper T cells (TH)/suppressor T cells (Ts) in the experimental group were significantly higher than those in the control group (P<0.05-0.001). At the 18th and 26th weeks, the total T cells (TG) and TH cells in the experimental group were significantly higher than those in the control group (P<0.05-0.01), and the Ts cells were significantly lower than the control group (P<0.05 to 0. 01). The results showed that Chinese medical stone can significantly increase the activity of IL-2 in HCC rats and prevent the change of T lymphocyte subsets. Its mechanism of action may be related to the rich trace elements in Chinese medical stone.