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目的:探讨脑外伤合并多脏器功能障碍的发病机制与综合治疗方法。方法:回顾性分析2000年3月～2009年6月我院NICU中收治的脑外伤合并多脏器功能障碍患者86例的临床资料。结果:394例脑外伤患者救治过程中出现多脏器功能障碍综合征86例(发生率为21.83%),其中死亡56例(病死率65.12%)。结论:及时有效地缓解颅内高压、恢复脑干功能是治疗的首要问题;而肺部继发症的合理治疗是控制多脏器功能障碍综合征的重要环节;综合救治策略仍然是降低病死率的关键手段。
Objective: To investigate the pathogenesis and comprehensive treatment of multiple organ dysfunction after traumatic brain injury. Methods: The clinical data of 86 patients with brain injury and multiple organ dysfunction admitted to our hospital from March 2000 to June 2009 were retrospectively analyzed. Results: In the treatment of 394 cases of traumatic brain injury, there were 86 cases of multiple organ dysfunction syndrome (the incidence was 21.83%), of which 56 cases died (case fatality rate 65.12%). Conclusion: Timely and effective relief of intracranial hypertension and recovery of brain stem function are the primary problems in the treatment. The rational treatment of pulmonary complications is an important part of the management of multiple organ dysfunction syndrome. The comprehensive treatment strategy is still to reduce the mortality The key means.