影响侧脑室脑膜瘤手术疗效的多因素分析

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目的:探讨影响侧脑室脑膜瘤手术疗效的因素,从而更好的促进侧脑室脑膜瘤的手术治疗。方法:回顾性分析侧脑室脑膜瘤显微手术30例的临床病理特征与预后情况,其中KPS>70分表示为预后良好,KPS≤70分表示为预后不良。对各性别、年龄、部位、肿瘤大小、病理分型及术后有无并发症因素与预后进行x2检验与用Logistic回归分析其影响因素。结果:单因素分析表明肿瘤部位、病理分型及术后有无并发症对侧脑室脑膜瘤的预后有明显影响,P<0.05,差异有统计学意义。经Logistic回归分析,最终进入模型的影响因素有2个,它们分别是肿瘤部位和术后有无并发症,其P值均小于0.05。结论:在显微手术下,侧脑室脑膜瘤大部分可以全切并取得了较好的远期疗效。肿瘤部位和术后有无并发症是影响预后的一个重要因素,及时处理并发症能显著地改善预后。 Objective: To explore the factors influencing the curative effect of lateral ventricular meningioma, so as to better promote the surgical treatment of lateral ventricular meningioma. Methods: The clinical and pathological characteristics and prognosis of 30 patients with lateral meningiomas were analyzed retrospectively. Among them, KPS> 70 was considered as good prognosis, and KPS≤70 was considered as poor prognosis. The gender, age, location, tumor size, pathological type and postoperative complications and prognosis of the factors for the x2 test and Logistic regression analysis of its influencing factors. Results: Univariate analysis showed that tumor location, pathological type and postoperative complications had a significant effect on the prognosis of lateral ventricular meningioma, P <0.05, the difference was statistically significant. Logistic regression analysis showed that there were 2 influencing factors in the final model, which were the tumor site and postoperative complications, respectively. The P values ​​were less than 0.05. Conclusion: Under microsurgery, most of the lateral ventricular meningioma can be cut completely and the long-term curative effect has been achieved. Tumor location and postoperative complications is an important prognostic factor, timely treatment of complications can significantly improve the prognosis.
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