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作者评定了吸入BDP治疗妊娠期严重哮喘的安全性。40例(45次妊娠)皮质类固醇依赖性哮喘妇女,分娩时年龄21~46岁,平均29.8岁。其中38次妊娠时患者于怀孕开始正在用BDP治疗,4次妊娠于怀孕头3月开始用BDP,余3次妊娠于怀孕4~9月用BDP,后者吸入量平均336ug/日(9.5口/日,每口含BDP42ug)。因严重慢性哮喘除用BDP外,37次妊娠时加用强的松(Pre)口服10~60mg/日,隔日1次。
The authors assessed the safety of inhaled BDP in the treatment of severe gestational asthma. Forty cases (45 pregnancies) of corticosteroid-dependent asthma women, aged 21 to 46 years old, average 29.8 years old. Among 38 pregnancies, the patients started treatment with BDP at the beginning of pregnancy. Four pregnancies started with BDP in the first trimester of pregnancy. The other three pregnancies received BDP from April to September of pregnancy with an average of 336 ug / day (9.5 / Day, each with BDP42ug). Due to severe chronic asthma in addition to BDP, 37 pregnancies plus prednisone (Pre) oral 10 ~ 60mg / day, every other day.