Tuberculosis (TB) is a contagious-infectious disease mainly caused by Mycobacterium tuberculosis.Antitubercular bioassay-guided fractionation of the chloroform extract of the leaves and stems of Ardis
Myrmekioside A, belonging to a new family of glycolipids with a unique structure of mono-O-alkyl-diglycosylglycerol, was isolated from a marine sponge of Myrmekioderma sp.and showed reversing effect o
Quinolizidine and indolizidine alkaloids have provided a rich source of synthetic targets because of their potential pharmaceutical applications1.Polyhydroxylated indolizidines have been desirable syn
Based on our well-established protocol for the preparation of N-aryl 2-aminophenols (1) from renewable nature product (-)-shikimic acid, an efficient method for the assembly of novel and diversified p
A series of furoxan-based nitric oxide-releasing chrysin and luteolin derivatives were synthesized.Pharmacological assays indicated that all chrysin and luteolin derivatives exhibited in vitro inhibit
Alkenal double bond reductases (DBRs) catalyze the NADPH-dependent reduction of the α,β-unsaturated double bond of many secondary metabolites.Two alkenal double bond reductase genes PaDBR1 and PaDBR2
A method for the direct arylation of 5-iodouracil and 5-iodouridine was found to proceed in moderate yields.By irradiating the 5-iodouracil or 5-iodouridine with a series of five-membered heterocycles