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以前认为局灶性节段性肾小球硬化症代表类脂性肾病的末期,但如今有大量证据揭示二者的病因不同,前者是一种进行性非增殖性肾脏病,伴有持久性镜下血尿,对激素无反应的蛋白尿,且往往有明显的肾病综合征。作者研究了16例患者,男性13例,女性3例,起病年龄15个月至44岁(中数21岁),5例小于10岁,3例超过25岁。均经肾活检确定诊断。初诊主诉7例水肿,1例头痛、血压高与蛋白尿;1例有排尿困难与尿液混浊;余7例尿常规有蛋白尿而无症状。4例血
Focal segmental glomerulosclerosis was previously considered to represent the end of lipid-induced nephropathy, but there is now a large body of evidence that suggests a different etiology between the two, a progressive nonproliferative nephropathy with persistent microscopic Hematuria, proteinuria that does not respond to hormones, and often has significant nephrotic syndrome. The authors studied 16 patients, 13 males and 3 females, with onset from 15 months to 44 years (median 21 years), 5 were younger than 10 years and 3 were older than 25 years. All confirmed by renal biopsy. The first visit complained of 7 cases of edema, 1 case of headache, high blood pressure and proteinuria; 1 case of dysuria and urine turbidity; more than 7 cases of urinary proteinuria without symptoms. 4 cases of blood