论文部分内容阅读
目的报道1例Osserman Ⅴ型重症肌无力患者,讨论其临床和肌肉病理特点。方法对1例Osserman Ⅴ型重症肌无力患者的临床特点进行回顾性分析,对患者行右侧肱二头肌的活体组织病理检查。结果该患者临床早期出现肌肉萎缩,球部症状明显。肌肉活检可见轻微肌源性和神经源性改变,同时合并有微血管病变。结论 Osserman Ⅴ型重症肌无力发病率低,充分认识其临床特点及肌肉病理特征,有利于提高诊断率,预测预后及合理治疗。
Objective To report a case of Osserman type Ⅴ myasthenia gravis and discuss its clinical and muscle pathological features. Methods A retrospective analysis was performed on the clinical features of Osserman type Ⅴ patient with myasthenia gravis. The biopsy of the right biceps was performed. Results The patient had muscular atrophy early in the clinical manifestations of bulbar symptoms. Muscle biopsy showed mild myogenic and neurogenic changes, combined with microvascular disease. Conclusion The incidence of Osserman type Ⅴ myasthenia gravis is low, and its clinical features and muscle pathology are fully understood. It is helpful to improve the diagnosis rate, prognosis and reasonable treatment.