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前列腺增生(Benign Prostatic Hyperplasial简称BPH)是老年男性常见的疾病和主要死亡原因之一。据统计,大于60岁的男性70％以上会发生病理性BPH(无阻梗症状),因此有人推论一个50岁的男子在他以后的生命中,有25～50％的机会需行前列腺切除术。几十年来,许多学者对BPH的病因进行了一系列研究,但确切原因尚不清楚,各种实验结果亦不尽一致。直至七十年代后放射免疫分析等方法的广泛应用,人们对BPH的病因才有了较深的认识,并在此基础上进行了药物治疗BPH新的尝试。“DHT学说”导致尿道梗阻的BPH仅发生在两个动物种类,
Benign Prostatic Hyperplasia (BPH) is one of the common diseases and main causes of death in elderly men. It is estimated that more than 70% of men over the age of 60 develop pathological BPH (non-infarct symptoms), so it is assumed that a 50-year-old man has a 25-50% chance of prostatectomy in his later life. For decades, many scholars have conducted a series of studies on the etiology of BPH, but the exact reasons for this are not yet clear, and the results of various experiments are not consistent. Until the seventies after radioimmunoassay and other methods of widespread use, people have a deeper understanding of the cause of BPH, and on this basis, a new attempt to drug treatment of BPH. “DHT theory” causes BPH of urinary tract obstruction occurs only in two animal species,