多发性肌炎(poly myositis,PM)是涉及多学科的一种肌肉炎性疾病。目前已积累的证据表明,PM是一自身免疫性疾病。随着基础免疫理论和免疫学技术的进展,有关本病免疫学研究取得了很大的进展。多发性肌炎免疫研究的变迁 PM最早是由Wagner于1863年报告,1887年由Unverricht命名为皮肌炎。以后又发现一些病例皮肤症状很轻甚至无皮肤症状,但却常常合并系统性红斑狼疮(SLE)、类风湿 Polymyositis (PM) is a multi-disciplinary, muscular inflammatory disease. There is now accumulated evidence that PM is an autoimmune disease. With the progress of basic immune theory and immunological technology, great progress has been made in the immunological research of this disease. The Evolution of Polymyositis Immune Study PM was first reported by Wagner in 1863 and by 1838 by Unverricht as dermatomyositis. Later found that some cases of skin symptoms are light or even no skin symptoms, but often combined systemic lupus erythematosus (SLE), rheumatoid