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为观察SARS患者血清白介素 - 8(IL - 8)含量变化 ,用放射免疫法检测了 6 6例SARS患者血清IL - 8含量 ,并与对照组作了比较。结果显示 ,SARS患者IL - 8含量明显高于对照组 ,恢复期血清IL - 8含量变化多样。结论 :SARS患者存在免疫反应异常 ,血清IL - 8含量变化可能在SARS发病机制中起重要作用
In order to observe the change of serum interleukin - 8 (IL - 8) in patients with SARS, the level of IL - 8 in serum of 66 patients with SARS was detected by radioimmunoassay and compared with the control group. The results showed that the content of IL - 8 in SARS patients was significantly higher than that in control group, and the levels of IL - 8 in convalescent patients varied greatly. Conclusion: There is an abnormal immune response in SARS patients, and the change of serum IL - 8 level may play an important role in the pathogenesis of SARS.