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对95例新发麻风病而无并发症的病人,用苏木素伊红染色方法,作了详细的组织病理学的研究。在显微镜下表现的特征,根据Ridley氏在1974年定下的标准来分类;而临床分类则系按照Ridley和Jopling两氏的1962年的标准。经比较,两种分类法的差异是明显的。在1/3的病例中两种分类法结果相符。而很多病例在光谱中趋向结核样型或瘤型。其余的归人未定类,因为它们只有早期的组织病理学变化。此种差异是予料到的,因为组织病理学分类法是准确的,而且具有免疫学方面的表现。组织病理学分类法似乎是比较实用的,因为不论是否接受治疗的病例,此分类法,都被证明是有效的。
A detailed histopathological study of 95 patients with new-onset leprosy without complications was performed using the hematoxylin and eosin staining method. The features under the microscope were classified according to Ridley’s criteria set in 1974; clinical classification was based on the 1962 criteria of Ridley and Jopling. By comparison, the difference between the two taxonomies is obvious. In one third of the cases, the results of the two taxonomies were consistent. Many cases tend to be nodular or neoplastic in the spectrum. The rest are classified as undeclared because they have only an early histopathological change. This difference is expected, because histopathological classification is accurate and has immunological aspects. Histopathological taxonomies seem to be more practical, as the taxonomic method has proven to be effective with or without treatment.