论文部分内容阅读
[目的]观察早期经三腔喂养管给药治疗重症急性胰腺炎的效果。[方法]按入院顺序随机将136例重症急性胰腺炎患者分为观察组与对照组。观察组为经内镜直视下行三腔喂养管给药组,对照组为常规行胃管给药组。分别检测2组患者在相同时间点的APACHEII评分、血清淀粉酶、超敏C反应蛋白水平,观察经不同途径给予中药时患者耐受程度、肠道动力功能恢复时间以及住院时间。[结果]观察组患者出现恶心、呕吐、腹痛加重的胃肠道症状发生率明显低于对照组(χ~2=15.4,P<0.01),观察组肠道功能恢复时间明显短于对照组(t=5.2417,P<0.05)。观察组患者在入院后第7天超敏C反应蛋白水平明显低于对照组(t=2.2415,P<0.05),且住院时间显著短于对照组(t=5.1394,P<0.05)。[结论]早期经三腔喂养管给药治疗重症急性胰腺炎能明显提高给药依从性,减少恶心、呕吐发生率,缩短肠道动力功能恢复时间,显著降低超敏C反应蛋白水平,缩短住院时间,使预后得到明显改善,是一种安全、有效的治疗方法。
[Objective] To observe the effect of early triad feeding tube in the treatment of severe acute pancreatitis. [Methods] According to the order of hospitalization, 136 patients with severe acute pancreatitis were randomly divided into observation group and control group. The observation group was undergoing endoscopic direct descending three-chamber feeding tube administration group, the control group was routine gastric tube administration group. The APACHEII score, serum amylase and high-sensitivity C-reactive protein level were detected at the same time points in two groups of patients. The patient tolerance, intestinal functional recovery time and hospital stay were observed by different ways. [Results] The incidence of gastrointestinal symptoms in the observation group was significantly lower than that in the control group (χ ~ 2 = 15.4, P <0.01). The recovery time of intestinal function in the observation group was significantly shorter than that of the control group t = 5.2417, P <0.05). On the 7th day after admission, the level of high-sensitivity C-reactive protein in observation group was significantly lower than that in control group (t = 2.2415, P <0.05), and the hospitalization time was significantly shorter than that in control group (t = 5.1394, P <0.05). [Conclusion] Early treatment of severe acute pancreatitis by triple-chamber feeding tube can obviously improve the administration compliance, reduce the incidence of nausea and vomiting, shorten the recovery time of intestinal motility, significantly reduce the level of hypersensitive C-reactive protein and shorten the length of hospital stay Time, so that the prognosis was significantly improved, is a safe and effective treatment.