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目的 :评估氟康唑联合制霉菌素治疗小儿鹅口疮的临床疗效。方法 :选取2015年我院诊断为鹅口疮的97例住院患儿,随机分为两组,对照组42例,观察组49例,治疗组予以氟康唑联合制霉菌素治疗,对照组单用制霉素治疗的48例此病患儿作对比研究。结果 :观察组与对照组患儿在症状改善、疗效、复发率以及不良反应率上均存在明显差异,P值小于0.05。结论 :氟康唑联合制霉菌素治疗小儿鹅口疮可缩短病程,减少复发率及不良反应率,疗效显著。
Objective: To evaluate the clinical efficacy of fluconazole combined with nystatin in the treatment of infantile thrush. Methods: A total of 97 inpatients diagnosed as thrush in our hospital in 2015 were randomly divided into two groups: control group (n = 42) and observation group (n = 49). The treatment group was treated with fluconazole combined with nystatin. Forty-eight cases of children with this disease for comparative study. Results: There were significant differences between the observation group and the control group in symptom improvement, efficacy, recurrence rate and adverse reaction rate, P value was less than 0.05. Conclusion: Fluconazole combined with nystatin treatment of pediatric thrush can shorten the course of disease, reduce the recurrence rate and adverse reaction rate, the curative effect is remarkable.