论文部分内容阅读
目的探讨糖尿病患者胆囊的运动功能。方法用超声对比观察22例正常对照和20例糖尿病人空腹胆囊大小、状态及脂肪餐后胆囊收缩半排空时间的差异。对其中6例有明显胆囊排空障碍的病人,给予西沙比利10mg,3次/d治疗4周后复查。结果正常对照与糖尿病组餐前胆囊面积无差异,但糖尿病人胆结石形成率高达30%(6/20),胆囊壁增厚、粗糙率为35%(7/20),明显高于正常对照组(P<005),餐后的胆囊半排空时间正常对照组为(27±4.4)min,而糖尿病组为(461±129)min,(P<0.05)。6名有排空障碍的糖尿病患者治疗前的半排空时间为(58.3±4.1)min,经治疗后半排空时间为(30±6.3)min,(P<0.01)。结论糖尿病患者有明确的胆囊排空运动障碍,并较多发生胆囊炎、胆石症,西沙经利可有效改善糖尿病患者的胆囊排空障碍。
Objective To investigate the motor function of gallbladder in diabetic patients. Methods Contrastive observation of 22 cases of normal control and 20 cases of diabetic patients with fasting gallbladder size, status and fat gallbladder contraction half-emptying time differences. 6 cases of patients with obvious gallbladder emptying disorders, giving cisapride 10mg, 3 times / d treatment for 4 weeks after the review. Results There was no difference in pre-meal gallbladder area between normal control group and diabetic group. However, the rate of gallstone formation in diabetic patients was as high as 30% (6/20) and the thickness of gallbladder wall was 35% (7/20), which was significantly higher than that of normal control (P <0.05). The median time to postprandial gallbladder half emptying was (27 ± 4.4) min in the control group and (461 ± 129) min in the diabetic group (P <0.05). Six patients with emptying disorder had a half-emptying time of (58.3 ± 4.1) min before treatment and a half-emptying time of (30 ± 6.3) min after treatment (P <0. 01). Conclusion Diabetic patients have clear gallbladder emptying dyskinesia, and more occurrence of cholecystitis, cholelithiasis, Xisha Jingli can effectively improve the gallbladder emptying disorders in patients with diabetes.