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目前治疗间质性膀胱炎方法很多,但尚无一种满意方法。作者报道阿霉素膀胱内灌注治疗间质性膀胱炎获得了明显的治疗效果,可在门诊进行,无明显副作用。典型溃疡型间质性膀胱炎3例(男2例,女1例),病史、膀胱镜及病理学检查均支持诊断。3例经抗生素治疗其尿培养阴性后,膀胱刺激症状及膀胱内病变仍持续存在。病检2周后,将50mg阿霉素溶于50ml生理盐水中,上导尿管捧空小便后,将上述药物注入膀胱。每隔15分钟变换一次体位,药物继续在膀胱内保留1小时,再随小便排出,开始每周1次,共6周;以后每月1次,共12
Currently there are many ways to treat interstitial cystitis, but there is not a satisfactory method. The authors report that intravitreous infusion of doxorubicin achieves significant therapeutic effects in the treatment of interstitial cystitis and can be performed in an outpatient setting without significant side effects. Typical ulcerative interstitial cystitis in 3 cases (2 males and 1 female), history, cystoscopy and pathological examination support the diagnosis. Three cases of negative urine culture after antibiotic treatment, bladder irritation and bladder lesions still persist. Two weeks after the disease examination, 50 mg of doxorubicin was dissolved in 50 ml of normal saline, and the catheter was emptied of urine and the above drugs were injected into the bladder. Every 15 minutes change position, the drug continued to retain 1 hour in the bladder, and then discharged with the urine, starting once a week for a total of 6 weeks; once a month after a total of 12