Sézary综合征(SS)是蕈样霉菌病(MF)一种变异类型。本文报告1例83岁男性,有5年典型的SS病史,先后用了两程电子束治疗(总量2600拉得)以及强的松和低剂量苯丁酸氮芥治疗,在5年中除中断9个月外,苯丁酸氮芥平均3mg/d,强的松10mg/d。后期伴发有顽固性尖锐湿疣及皮肤多处鳞癌,并作了局部切除。在此次肺播散前,SS仅显轻微活动,无肺部症状,3个月前胸片正常。此次入院是因突然发生双肺浸润(有照片证 Sézary’s syndrome (SS) is a variant of mycosis fungoides (MF). This article reports an 83-year-old man with a 5-year history of typical SS disease treated sequentially with two-way electron beam therapy (totaling 2,600 d) and prednisone and low-dose chlorambucil, Nine months off, chlorambucil average 3mg / d, prednisone 10mg / d. Late with persistent refractory genital warts and skin multiple squamous cell carcinoma, and made a partial resection. Before the lungs were disseminated, SS was only slightly active, with no symptoms of the lungs, and chest radiographs were normal 3 months earlier. The admission is due to a sudden infiltration of both lungs (photo card