子宫内膜异位症常常合并不孕,国内外学者经过多年的研究,提出种种的学说,均未能弄清其根本的原因,尤其是轻型的患者,输卵管卵巢功能未受破坏,有的患者生育能力受影响,有的却未受影响,说明其中尚有未知的个体差异,有几种机制曾被用来解释不孕的原因:如腹腔液中前列腺素浓度升高,被激活的巨噬细胞增多,雌孕激素偏低,排卵机能不全,黄素化未破裂卵泡综台征(LUF),黄体不健,高PRL血症等。80年代以来的研究比较集中于免疫学的问题,Weed 及Arquenbourg 等1980年前先提出子宫内膜异位症可产生一种自身免疫反应,异位的宫内膜及经血,在被巨噬细胞吞噬及清除的过程中,内膜抗原部分被转移至网状内皮系统,刺激淋巴细胞而产生抗内膜抗体,这些抗体在补体的参与下作用于自身靶器 Endometriosis often associated with infertility, domestic and foreign scholars after years of research, put forward a variety of doctrines, failed to find out its fundamental causes, especially in patients with light, tubal ovarian function is not damaged, and some patients Fertility affected, and some are not affected, indicating that there are still unknown individual differences, there are several mechanisms have been used to explain the reasons for infertility: such as elevated concentrations of prostaglandin in the peritoneal fluid, activated macrophages Increased cells, low estrogen and progesterone, ovulation insufficiency, luteinized unruptured follicle syndrome (LUF), corpus luteum, high PRL hyperlipidemia. 80s since the study focused on immunological issues, Weed and Arquenbourg before 1980 proposed that endometriosis can produce an autoimmune reaction, ectopic endometrium and menstrual blood, by macrophages During phagocytosis and clearance, portions of the intima-antigen are transferred to the reticuloendothelial system to stimulate lymphocytes to produce anti-intima antibodies that act on their own targets with the involvement of complement