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目的 研究在部队中HCV感染者的发展与转归及可能对周围人群传播的危险性。方法 采用回顾性 和前瞻性调查研究,对604名军校学员采空腹静脉血用ELISA法检测抗-HCV,并对抗-HCV阳性者的血液、痰液、唾液和汗液,用聚合酶链反应检测HCV-RNA,计算其感染率。结果 部队人群HCV总感染率为1.16％,低于全国平均2.15％的水平,3年追踪调查,没有发现临床肝炎患者,也未发现有肝炎症状和体征的人。观察期间感染者抗-HCV始终为阳性。HCV隐性感染者有可能作为传染源通过生活接触导致传播,但只引起隐性感染。研究还表明:通过入伍前在地方查体和入伍后健康查体,基本能防止大多数丙肝病人进入部队,丙肝隐性感染者一般不会对部队卫生管理带来严重后果。
Objective To study the development and prognosis of HCV infection in the army and the potential risk of spreading to the surrounding population. Methods A retrospective and prospective study of 604 cadets taking fasting venous blood was used to detect anti-HCV by ELISA and anti-HCV positive for blood, sputum, saliva and sweat by polymerase chain reaction -RNA, calculate the infection rate. Results The total HCV prevalence in the army was 1.16%, lower than the national average of 2.15%. Three years of follow-up investigation revealed no clinical hepatitis and no symptoms or signs of hepatitis. Infected during the observation of anti-HCV is always positive. It is possible that latent infection with HCV can cause transmission through contact with life as a source of infection but only cause a latent infection. The study also shows that most people with hepatitis C are generally unlikely to have any serious consequences on the health management of their troops, since the majority of patients with hepatitis C are prevented from entering the army by local physical examination and post-enlistment health checkup before enlistment.