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目的:探讨四维超声时空关联成像技术筛查中孕早期胎儿先天性心脏病的临床价值。方法:将我院自2013年11月至2016年9月间接受检查的3125例中孕早期孕妇作为研究对象,先行二维超声检查,记录出现异常的病例数,对68例孕妇行四维超声时空关联成像技术筛查(STIC),对比两种方法的疾病筛查率,总结STIC筛查的准确性和临床价值。结果:3125例孕妇中14例被确诊为心脏畸形,二维超声检测阳性率为64.29%,STIC阳性率为85.71%,二维超声与STIC联合检查阳性率高达92.86%,三种诊断方法比较差异具有统计学意义(P<0.05);二维超声样本耗时时间和每幅图像所用的时间均显著多于而STIC检查,组间比较差异具有统计学意义(P<0.05)。结论:使用四维超声时空关联成像技术检测中孕早期胎儿心脏畸形具有较高的临床价值,获得的动态图像准确率高,阳性检出率高,可为临床治疗提供依据。
Objective: To investigate the clinical value of four-dimensional ultrasound-SPECT imaging in the detection of fetal congenital heart disease in early pregnancy. Methods: From March 2013 to September 2016 in our hospital, 3125 pregnant women with early pregnancy in the first trimester were examined by two-dimensional ultrasonography. The number of abnormal cases was recorded. 68 pregnant women underwent four-dimensional ultrasound space-time Associated Imaging Technology Screening (STIC), comparing the disease screening rates of the two methods and summarizing the accuracy and clinical value of STIC screening. Results: Among 3125 pregnant women, 14 cases were diagnosed as heart deformity. The positive rate of two-dimensional ultrasonography was 64.29% and the positive rate of STIC was 85.71%. The positive rate of two-dimensional ultrasonography and STIC was 92.86% (P <0.05). The two-dimensional ultrasound time-consuming and time spent on each image were significantly more than STIC, the difference between the two groups was statistically significant (P <0.05). Conclusion: It is of high clinical value to detect fetal heart deformity in the first trimester by using the four-dimensional ultrasound spatio-temporal correlation imaging technique. The acquired dynamic images have high accuracy and high positive detection rate, which may provide the basis for clinical treatment.