目的　探讨慢性阻塞性肺疾病 (COPD)并发肺部真菌感染的危险因素、诊断和治疗。方法　回顾性分析COPD并发肺部真菌感染 2 6例的临床资料。结果　COPD并发肺部真菌感染的危险因素为 :长期使用广谱抗菌药物及糖皮质激素 ,老年病人和合并糖尿病、肺结核等慢性基础疾病病人多见。结论　合理使用抗菌药物及糖皮质激素、及时早期诊断和抗真菌治疗 ,是降低COPD并发肺部真菌感染的重要措施。 Objective To investigate the risk factors, diagnosis and treatment of pulmonary fungal infection in patients with chronic obstructive pulmonary disease (COPD). Methods The clinical data of 26 patients with COPD complicated with pulmonary fungal infection were retrospectively analyzed. Results The risk factors of COPD with pulmonary fungal infection were as follows: Long-term use of broad-spectrum antibiotics and glucocorticoids, elderly patients and patients with chronic basic diseases such as diabetes and tuberculosis were more common. Conclusion The rational use of antimicrobial agents and glucocorticoids, early diagnosis and antifungal therapy in time is an important measure to reduce COPD complicated with pulmonary fungal infection.