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目的观察热毒宁注射液对肺炎支原体肺炎患儿血清嗜酸性粒细胞(EC)及超敏C反应蛋白(hs-CRP)的影响。方法选择2009年1月-2011年12月在湖北省中山医院儿科门诊就诊的肺炎支原体肺炎患儿54例,随机分为治疗组和对照组,每组各27例,两组均予阿奇霉素治疗,治疗组在此基础上加用热毒宁注射液治疗,治疗7 d。观察两组患儿治疗效果,并比较两组患儿治疗前后血清EC和hs-CRP含量。结果治疗组疗效明显优于对照组(P<0.05),治疗后,治疗组患儿血清EC和hs-CRP含量均明显低于对照组,差异有统计学意义(P<0.05)。结论热毒宁治疗肺炎支原体肺炎具有良好的疗效,其机制可能与降低患儿血清EC和hs-CRP含量有关。
Objective To observe the effects of Rendunning Injection on serum eosinophil (EC) and high-sensitivity C-reactive protein (hs-CRP) in children with Mycoplasma pneumoniae pneumonia. Methods From January 2009 to December 2011, 54 children with mycoplasma pneumoniae pneumonia were treated in pediatric outpatient department of Zhongshan Hospital of Hubei Province. They were randomly divided into treatment group and control group, with 27 cases in each group. Both groups were treated with azithromycin, On the basis of this, the treatment group was treated with Renduining injection for 7 days. The therapeutic effects of the two groups of children were observed, and the levels of serum EC and hs-CRP were compared between the two groups before and after treatment. Results The treatment group was significantly better than the control group (P <0.05). After treatment, the levels of serum EC and hs-CRP in the treatment group were significantly lower than those in the control group (P <0.05). Conclusion Renduining treatment of Mycoplasma pneumoniae pneumonia has a good effect, and its mechanism may be related to reducing serum levels of EC and hs-CRP in children.