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为了能早期诊断卵巢癌，改善其预后，提高其生存率。本文应用ＥＬＩＳＡ测定了２５６例血清中ＣＡ１２５抗原，其中包括卵巢癌２７例，卵巢癌术后随访１２例，其它癌１２例，妇科良性肿瘤７８例，其它妇科疾病２３例及正常对照组１０４例。结果显示，２７例卵巢癌其ＣＡ１２５抗原检出率为９３％（２５／２７），２５６例血清样品灵敏度测定为８２％，特异性为７９％，总诊断有效率达８０％。结果提示ＣＡ１２５抗原ＥＬＩＳＡ法测定可能对卵巢癌的早期诊断及疗效观察有一定临床意义。
In order to early diagnosis of ovarian cancer, improve its prognosis and improve its survival rate. In this paper, we measured the serum CA125 antigen in 256 cases, including 27 cases of ovarian cancer, 12 cases of ovarian cancer followed up, 12 cases of other cancers, 78 cases of benign gynecologic tumors, 23 cases of other gynecological diseases and 104 cases of normal control group. The results showed that the detection rate of CA125 antigen was 93% (25/27) in 27 cases of ovarian cancer. The sensitivity and specificity of 256 serum samples were 82%, 79% and 80% respectively. The results suggest that CA125 antigen ELISA assay may have early diagnosis of ovarian cancer and the efficacy of clinical observation has some clinical significance.