用沙门氏菌50115号菌对银鲫(Caiassius auratus gibelio)及小白鼠(km)攻毒(7.5×10~8个菌感染)成功,而且鱼对该菌比小白鼠更敏感,症状更突出;银鲫的24hLD_(50)为3×10~7个/ml;抑制实验结果表明红霉素、痢特灵、庆大霉素、二氯异氰尿酸钠对该菌有抑制作用;把二氯异氰尿酸钠、痢特灵、红霉素、三种药物按0.4ppm、1ppm、0.4ppm 三种剂量对病鱼进行药浴,并结合投喂相应药饵,治愈率分别为60%、100%、80%。 Salmonella typhimurium 50115 was successfully challenged with Caiassius auratus gibelio and murine (7.5 × 10 ~ 8 bacteria), and the fish were more sensitive to the bacteria than the mice and the symptoms were more prominent. (50 ×) for 3 × 10 ~ 7 / ml. The results of inhibition experiments showed that erythromycin, furazolidone, gentamicin and sodium dichloroisocyanurate inhibited the fungus. Sodium urate, furazolidone, erythromycin, three drugs according to 0.4ppm, 1ppm, 0.4ppm three doses of diseased fish medicated bath, combined with feeding the corresponding drug bait, the cure rates were 60%, 100% 80%.