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顺铂抗癌谱广,疗效可靠,临床应用广泛,但其所致的严重胃肠道反应(恶心、呕吐)使病人难以耐受化疗,以往用胃复安等止吐效果差,且有明显锥体外系症状。近十余年来临床广泛使用半衰期长和高选择性的5-HT3受体拮抗剂格拉司琼等,能有效控制肿瘤患者化疗引起的恶心呕吐。我们应用格拉
Cisplatin has wide anti-cancer spectrum, reliable curative effect and wide clinical application. However, its serious gastrointestinal reaction (nausea and vomiting) makes it difficult for patients to tolerate chemotherapy. In the past, antiemetic effect of cisplatin was poor and obvious. Extrapyramidal symptoms. Nearly ten years of extensive clinical use of long-term and high selectivity of 5-HT3 receptor antagonist granisetron and so on, can effectively control cancer patients with chemotherapy-induced nausea and vomiting. We use Gela