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设计并合成了9种未见文献报道的N-(5-邻氯苯基-2-呋喃甲酰氨基硫羰基)-L-α-氨基酸乙酯衍生物,其结构经IR,1HNMR,MS和元素分析测试确证.MTT法测试结果表明大部分目标化合物对白血病K562细胞系的增殖具有明显的抑制作用.
Nine new derivatives of N- (5-chlorophenyl-2-furidoylaminothiocarbonyl) -L-α-amino acid have been designed and synthesized. Their structures have been characterized by IR, 1HNMR, MS and Elemental analysis confirms the test.MTT test results show that most of the target compounds have a significant inhibitory effect on the proliferation of leukemia K562 cell line.