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胃癌高发区饮水作用于体外长期培养的人胚胃成纤维细胞后,FCM分析发现S和G2M期细胞比例和增殖指数明显增加,DNA指数超出正常范围,细胞有明显的形态学改变,这些结果提示该县饮水可能有致癌性,可能与当地胃癌高发有密切关系。
After drinking water in high-incidence areas of gastric cancer and acting on human embryonic stomach fibroblasts cultured in vitro for a long time, FCM analysis showed that the proportion of cells and proliferation index in S and G2M phases increased significantly, the DNA index exceeded the normal range, and the cells had obvious morphological changes. These results suggest that Drinking water in this county may be carcinogenic and may be closely related to the high incidence of local gastric cancer.