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目的:探讨我院喹诺酮类药的应用状况。方法:对我院2007～2009年喹诺酮类药的应用品种、销售金额、用药频度(DDDs)、日均费用(DDC)以及细菌耐药性等进行统计、分析。结果:3年来喹诺酮类药总销售金额逐年上升,年增长率分别为18.89%和3.24%。口服喹诺酮类药的DDDs逐年上升,注射用喹诺酮类药的DDDs 2009年略有下降,左氧氟沙星销售金额及DDDs居于首位。3年中5种主要病原菌对部分喹诺酮类药的耐药率超过60%。结论:我院喹诺酮类药耐药率较高,临床应用仍需进一步加强监督管理。
Objective: To investigate the application of quinolones in our hospital. Methods: The types and sales amount of quinolones, DDDs, DDC and bacterial resistance in our hospital from 2007 to 2009 were analyzed statistically. Results: The total sales of quinolone drugs increased year by year in three years with annual growth rates of 18.89% and 3.24% respectively. The DDDs of oral quinolones increased year by year. The DDDs of quinolones for injection dropped slightly in 2009, and the sales amount of levofloxacin and DDDs ranked the first place. The resistance of 5 major pathogens to some quinolones over 3 years exceeded 60%. Conclusion: The quinolone resistance in our hospital is high, so the clinical application still needs to be further strengthened.