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目的:探讨观察围生期下肢深静脉血栓形成孕产妇的临床特征和预后方法,有效降低孕产妇下肢深静脉血栓的形成。方法:收集2010年1月至2015年12月间我院60例围生期下肢深静脉血栓孕产妇患者的临床资料,对孕产妇发生下肢深静脉血栓的时间、发生部位、危险因素、临床表现、影像学检查、治疗方案和母婴结局等进行分析,总结其临床特征。结果:1发生时间:发生在围产期19例,占31.67%,妊娠时间为4~31周,平均12.5周;发生在产褥期41例,占68.33%,产后时间4~40d,平均26.2d。2发生部位:发生在左下肢的有51例,占85%,发生在右下肢的有9例,占15%。3危险因素:围生期不定期检查、产妇年龄或高或低、长时间卧床、合并症较多、有DVT病史或血栓家族史等是下肢深静脉血栓形成的关键危险因素。4临床症状:患者患肢肿胀、疼痛、压痛,出现不同程度的发热症状。5辅助检查:60例下肢深静脉血栓孕产妇均接受彩色多普勒超声检查确诊,D-二聚体阳性(55例)对于下肢深静脉血栓有良好的临床诊断价值。结论:围生期不定期检查、产妇年龄或高或低、长时间卧床、合并症较多、有DVT病史或血栓家族史等是下肢深静脉血栓形成的关键危险因素,而全身抗凝治疗和溶栓治疗对下肢深静脉血栓的临床疗效显著,值得借鉴应用。
Objective: To observe the clinical characteristics and prognosis of pregnant women with perinatal lower extremity deep vein thrombosis and to reduce the formation of deep vein thrombosis in pregnant women. Methods: The clinical data of 60 pregnant women with perinatal lower extremity deep vein thrombosis in our hospital from January 2010 to December 2015 were collected. The time, location, risk factors and clinical manifestations of lower extremity deep vein thrombosis in pregnant women were collected. , Imaging studies, treatment programs and maternal and infant outcomes were analyzed to summarize its clinical features. Results: 1 occurred in 19 cases of perinatal period, accounting for 31.67%, pregnancy time was 4 to 31 weeks, an average of 12.5 weeks; occurred in the puerperium 41 cases, accounting for 68.33%, postpartum time 4 ~ 40d, an average of 26.2d. 2 Occurred parts: occurred in the left lower limb in 51 cases, accounting for 85%, occurred in the right lower limb in 9 cases, accounting for 15%. 3 risk factors: non-scheduled perinatal examination, maternal age high or low, prolonged bed rest, more complications, history of DVT or family history of thrombosis is a key risk factor for lower extremity deep vein thrombosis. 4 clinical symptoms: patients limb swelling, pain, tenderness, there are different degrees of fever symptoms. 5 Auxiliary examination: 60 cases of lower extremity deep venous thrombosis were confirmed by color Doppler ultrasound examination of pregnant women, D-dimer-positive (55 cases) for the lower extremity deep venous thrombosis have a good clinical diagnostic value. Conclusions: Insufficient perinatal examination, maternal age, high or low, long time bed rest, more complications, DVT history or family history of thrombosis are the key risk factors for lower extremity deep vein thrombosis, and systemic anticoagulation therapy and Thrombolytic therapy of deep venous thrombosis of the clinical efficacy of significant, it is worth learning from.