ALDH2相关论文
目的：探索不同冠脉病变支数组乙醛脱氢酶2（ALDH2）基因型分布特点与CRP、SOD及NLR水平是否有差异，并分析不同基因型对介入治疗预后的影......
＜正＞肺结核是由结核分枝杆菌感染引起的一种肺部慢性传染性疾病，严重威胁人类健康安全，全球每年约有400万人死于该病，我国肺结核患者数......
目的 探讨瞬时受体电位锚蛋白亚型1受体（transient receptor potential ankyrin 1, TRPA1）在远端创伤预处理（RPCT）保护心肌缺血/再灌注......
Mitochondrial aldehyde dehydrogenase(ALDH2)rescues cardiac contractile dysfunction in an APP/PS1 mur
Alzheimer\'s disease(AD)is associated with high incidence of cardiovascular events but the mechanism remains elusive.O......
目的:观察益气活血法对胸痹心痛病(劳力性心绞痛)合并冠脉慢血流在不同ALDH2表型患者的疗效.方法:选择诊断为胸痹心痛病(劳力性心......
目的:酒精性肝病（ALD）是全球50%肝硬化病例的罪魁祸首,而过量饮酒的人群中50%以上会发生酒精性脂肪肝（AFLD）。在中国,一些地区ALD的患......
研究背景:WHO发布的《Global status report on alcohol and health 2018》显示:2016年全球约有60万人死于酒精相关消化系统疾病,4......
研究背景和目的急性心肌梗死（AMI）后随之出现的左心功能不全和心脏衰竭,具有较高的发病率和死亡率[1]。心梗后临床干预措施是有效地......
Neuroprotective effects of Alda-1 mitigate spinal cord injury in mice: involvement of Alda-1-induced
Spinal cord injury (SCI) is associated with high production and excessive accumulation of pathological 4-hydroxy-trans-2......
Mitochondrial aldehyde dehydrogenase 2 protects gastric mucosa cells against DNA damage caused by ox
ALDH2 is a member of aldehyde dehydrogenase superfamily that implicates in metabolic processes of aldehydes.ALDH2 plays ......
目的：观察低剂量乙醇干预对糖尿病大鼠心肌纤维化的影响，分析糖尿病心肌纤维化与线粒体ALDH2 水平之间的关系，并探讨ALDH2 是否通过JN......
To observe the changes of cardiac ALDH2 in diabetic rat, especially when diabetic rat was pretreated with ALDH2 activato......
目的 分析乙醛脱氢酶2(ALDH2)基因多态性与酒精性肝病(ALD)患者饮酒特点与疾病发生的关系。方法 采用TaqMan荧光定量PCR法，对无血缘......
Protective Effects and Mechanisms of Antrodia Cinnamomea and Its Compound Dehydroeburicoic Acid 32 o
Alcoholic fatty liver disease(AFLD)is the leading cause of chronic liver disease worldwide.An early response of the live......
Meta-analysis of relationship between CYP2E1 and ALDH2polymorphisms and hepatocellular carcinoma ris
The cytochrome P450 2E 1 (CYP2E1) and aldehyde dehydrogenase 2 (ALDH2) have been demonstrated that they were related to ......
By applying two-dimensional fluorescence difference gel electrophoresis (2D-DIGE) combined with MALDI-TOF/TOF tandem mas......
目的：探讨ALDH2在急性百草枯(paraquat,PQ)中毒致急性肺损伤(acute lung injury,ALI)作用的研究.方法：健康清洁级雄性SD大鼠120只(20......
Objective: Alcohol dehydrogenase-1B(ADH1B)and aldehyde dehydrogenase-2(ALDH2)genes are closely correlated with liver alc......
BDNF-TrkB pathway mediates the protection of hydrogen sulfide against formaldehyde-induced neurotoxi
[Backgroud and Objective] Formaldehyde (FA) can induce neurotoxicity.We have previously found that Hydrogen sulfide (H2S......
ALDH2是编码乙醛脱氢酶的重要基因,但存在单核苷酸多态性(single nucleotidepolymorphism,SNP)位点(rs671位点,G＞A),其中ALDH2*1等......
The role of ALDH2 in tumorigenesis and tumor progression:Targeting ALDH2 as a potential cancer treat
A major mitochondrial enzyme for protecting cells from acetaldehyde toxicity is aldehyde dehydrogenase 2 (ALDH2).The cor......
本课题研究的是利用高分辨率熔解曲线(HRM)技术分辨人体中线粒体乙醛脱氢酶2(ALDH2)是否变异,从而达到对每个个体进行饮酒能力预测......
利用生物信息学方法预测出miR-224可能的靶基因为ACADM、ACAT1、ALDH2和LPL,然后用实时荧光定量法检测了miR-224与其靶基因在奶牛......
目的探讨2型糖尿病(T2DM)合并冠心病患者血栓前状态(PTS)与ALDH2基因多态性的相关性。方法将140例T2DM合并冠心病患者作为研究组,1......
ALDH2是编码乙醛脱氢酶的重要基因,但存在单核苷酸多态性(single nucleotide polymorphism,SNP)位点(rs671位点,G＞A),其中ALDH2......
目的本课题旨在确定ALDH2和GSTM1基因多态性与食管癌易感性的关系,以便采取有针对性的预防措施,降低食管癌的发生率。方法用病例对......
目的:探讨携带乙醛脱氢酶2(Aldehyde dehydrogenase 2,ALDH2)rs671单核苷酸多态性(single nucleotide polymorphism,SNP)的个体ALD......
背景:氧化应激和神经元凋亡在蛛网膜下腔出血(subarachnoid hemorrhage,SAH)后早期脑损伤(early brain injury,EBI)的发病机制中起......
背景和目的根据GLOBOCAN 2018统计数据,目前全球范围内癌症发病率和死亡率依然处于迅速增长阶段。无论是从发病率还是死亡率来看,......
肝脏移植是治疗终末期肝脏疾病的最常用且最有效的治疗手段,而肝脏缺血再灌注损伤(ischemia-reperfusion injury,IRI)是肝移植过程......
The relationship between polymorphisms at the alcohol dehydrogenase 2 (ADH2), ADH3,CYP 4502E1 and aldehyde dehydrogenase......
目的 研究ALDH2基因与酒精代谢之间的关联性实验中,采用芯片检测法检测ALDH2基因的不同基因型,探讨芯片检测的原理及其方法,评......
目的 乙醛脱氢酶2 (aldehyde dehydrogenase 2,ALDH2),为乙醛脱氢酶家族成员之一,是一种主要由位于线粒体基质染色体12q24编码......
酒精在体内的第一级代谢产物一乙醛具有明确的心肌毒性。乙醛脱氢酶2(ALDH2)是体内重要的醛类代谢酶，但ALDH2在酒精性心肌损伤......
目的 系统评价ALDH 2基因多态性与缺血性脑卒中的关系.方法 计算机检索Web of Science、PubMed、CNKI、CBM和WanFang Data数据库,......
目的研究线粒体乙醛脱氢酶2(ALDH2)缺失对体外培养的小鼠骨髓内皮祖细胞(EPCs)生长状态及功能的影响。方法分别取C57BL/6小鼠(WT)......
