Proteostasis (protein homeostasis) ensures precise adjustment of cellular demand to proteins in the stress conditions,wh......

Cells have different sets of molecules for performing an array of physiological functions.Nu-cleic acids have stored and......

Background: The SWI/SNF complex is a central ATPase dependent chromatin remodeling complex that is conserved from yeast ......

With an aging society in the speed,improvement of the physical function status and quality of life is more meaningful th......

Cancer cells endure higher internal proteotoxic stresses through upregulating protein quality control components,regulat......

Maintaining proteostasis is an essential housekeeping function for cell survival.It involves chaperones and degradative ......

　　Alzheimers disease (AD) is a rising threat for modern societies as more and more people reach old age.To date,there ......

Many neurodegenerative diseases are characterized by impairment of protein quality control mechanisms in neuronal cells.......

Proteins fold into their functional 3-dimensional structures from a linear amino acid sequence. In vitro this process is......