pluripotency相关论文
GATA4, as a member of the GATA transcription factor family, plays a significant role in lineage specification and trans-......
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Plasticity of male germline stem cells and their applications in reproductive and regenerative medic
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Embryonic stem (ES) cells was isolated from blastocysts and grown as a cell line in culture.ES cells are pluripotent cel......
To better understand how Nanog functions in regulating self-renewal and maintaining pluripotency,we report in this study......
Jmjd1a and Jmjd2c are well-known epigenetic regulators that play significant role in stem cell identity through demethyl......
Oct4 heterodimerizes with Sox2 to direct a gene expression program establishing pluripotency.Oct4 also possess a lesser-......
Next generation unnatural monosaccharides reveal that FSRRB O-GlcNAcylation regulates pluripotency o
Unnatural monosaccharides such as azidosugars that can be metabolically incorporated into cellular glycans are currently......
Redox state mediates embryonic stem cell (ESC) differentiation and thus offers an important complementary approach to un......
Pluripotent stem cells (PSCs) can be expanded in vitro in different culture conditions, resulting in a spectrum of cell ......
Super-enhancers (SEs) comprise large clusters of enhancers,which are co-occupied by multiple lineage-specific and master......
Acidic pH transiently prevents the silencing of self-renewal and dampens microRNA function in embryo
Enhanced glycolysis is a distinct feature associated with numerous stem cells and cancer cells.However,little is known a......
Hepatocellular carcinoma(HCC)is a leading cause of cancer deaths.It is often detected at a stage when there are few ther......
Cancer stem cells(CSCs)are tumor cells that share functional characteristics with normal and embryonic stem cells.CSCs h......
Aurora kinase B and C differentially regulate mitosis and cell fate in mouse preimplantation embryos
Aurora kinases are evolutionarily conserved serine/threonine kinases and key regulators of mitosis.Aurora kinase B i......
Cardiomyocyte differentiation in vitro system from zebrafish embryos remains to be established.Here,we have determin......
在 2006， Shinya Yamanaka 在房间出版的一篇文章使干细胞研究社区大吃一惊。由执行系统的制动火箭，因素的病毒的 transduction 在胚......
LIN28A inhibits DUSP family phosphatases and activates MAPK signaling pathway to maintain pluripoten
LIN28A,an RNA-binding protein,plays an important role in porcine induced pluripotent stem cells(piPSCs).However,the mole......
Biological reactions require self-assembly of factors in the complex cellular milieu.Recent evidence indicates that intr......
目的 :建立猪naive-like诱导性多能干(induced pluripotent stem,i PS)细胞系,并对其进行红色荧光标记,为通过示踪猪naive i PS细......
Epigenetic reprogramming provides valuable resources for customized pluripotent stem cells generation,which are thought ......
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Human pluripotent stem cells (hPSCs) are an important system to study early human development,model human diseases,and d......
Peach palm (Bactris gasipaes Kunth) has been micropropagated from pre-procambial cells that provide stem-like cell niche......
,PCGF6 regulates stem cell pluripotency as a transcription activator via super-enhancer dependent ch
Polycomb group (PcG) ring finger protein 6 (PCGF6),though known as a member of the transcription-repressing complexes,Pc......
Induced pluripotent stem(iPS)cells can be generated by forced expression of four pluripotency factors in somatic cells.T......
The advent of induced pluripotent stem cells(iPSCs)has revolutionized the concept of cellular reprogramming and potentia......
本文通过对荣华二采区10...
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
Acquisition of pluripotency in the chick embryo occurs during intrauterine embryonic development a u
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Fluorescent nanoswitch for monitoring specific pluripotency-related microRNAs of induced pluripotent
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的 获取SD大鼠胚胎中附植后的胚胎上胚层干细胞(EpiSCs),并就影响SD大鼠EpiSCs(SDEpiSCs)分离与培养的组织来源、胎龄、细胞因子......
Objective To clone, express, purify human Oct-4 and detect its subcellular localization.Methods Human Oct-4 cDNA was amp......
In vitro cultured embryonic stem (ES) cells are derived from the inner cell mass (ICM) of pre-implantation embryos, and ......
The recent progress in derivation of pluripotent stem cells(PSCs)from farm animals opens new approaches not only for rep......
Activation of paternally expressed imprinted genes in newly derived germline-competent mouse parthen
单性生殖的胚胎的茎(足) 细胞为学习位于印的 genomic 下面的分子的机制提供一个珍贵试管内模型系统。然而，足房间的 thepluripoten......
在 pluripotency 的正式就职的核心管理者最近在体的房间 reprogramming 期间被发现了的 Yamanaka 因素的角色。我们的以前的学习......
Yamanaka factors critically regulate the developmental signaling network in mouse embryonic stem cel
Yamanaka 因素(Oct3/4， Sox2， Klf4， c-Myc ) 高度在胚胎的茎(ES ) 被表示房间，和他们的在表示上能在老鼠和人的体的房间导致 pluripot......
为研究Survivin对维持胚胎干细胞（ES细胞）多潜能性的影响,用1 μmol/L RA作为培养条件诱导ES细胞分化,通过Western blot与real-time ......
Pancreatic ductal adenocarcinoma(PDAC),the most common type of pancreatic tumor,is a highly aggressive human cancer with......
使用免疫荧光技术检测与增值、凋亡、多能性相关基因的表达水平。提高bFGF浓度可增强PCNA、Oct-4、Sox-2、Bax和Bcl-2的表达，同时使......
实验共设计了8对引物,即发育全能性的标志基因（OTC4）引物1对,管家基因（β-actin）引物1对,三胚层分别特异表达的基因引物各2对。每个胚......
神经干细胞可持续增殖、分化产生神经元、星型胶质细胞和少突胶质细胞.神经干细胞的这种特性为进行中枢神经退行性病变和损伤的治......
The study of embryonic stem cells is in the spotlight in many laboratories that study the structure and function of chro......
AIM:To examine the imprinted Dlk1-Dio3 locus in pluripotent embryonic stem(ES)cell/fibroblast hybrid cells.METHODS:Gtl2,......
