trifluoromethyl相关论文
Organic compound bearing a trifluoromethyl(CF3)group play an increasingly important role in medicine fields [1,2]....
发展了一个无光敏剂参与的可见光促进的咪唑并[1,2-a]吡啶衍生物的三氟甲基化新反应.该反应利用本课题组此前发展的基于硫叶立德骨......
Rational Design and Development of Low-Price,Scalable,Shelf-Stable and Broadly Applicable Electrophi
Main observation and conclusionrnThe development of two highly reactive electrophilic trifluoromethylating reagents(trif......
Rational design of new bioisosteres through introduction of high-value functional groups to bicyclo[1.1.1]pentane (BCP) ......
Syntheses, Crystal Structures, and Antitumor Activities of Two 2-Trifluoromethyl-5,6,7,8-tetrahydrob
本文通过对荣华二采区10...
Synthesis, Crystal Structure, and Antitumor Activity of 1-(4-Methoxybenzylidene)-2-(1-phenyl-6-trifl
本文通过对荣华二采区10...
Syntheses, Crystal Structures, and Biological Activities of Two Enantiomeric 2-Trifluoromethylthieno
Two enantiomeric 2-trifluoromethyl-6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-amine derivatives were synthes......
Bronsted Acid Mediated (sp3)Carbon-Fluorine Bond Activation: Inter-and Intramolecular Arylation of T
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
A General and Highly Selective Method for the Asymmetric Synthesis of Trifluoromethyl-Substituted α-
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Facile synthesis of novel fluorinated thieno[2,3-d]pyrimidine derivatives containing 1,3,4-thiadiazo
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
An aromatic diamine monomer, 4,4'-bis(3-amino-5-trifluoromethyl phenoxy)-biphenyl (TFBPDA), was synthesized via the nucl......
Facile synthesis of novel fluorinated thieno[2,3-d]pyrimidine derivatives containing 1,3,4-thiadiazo
A series of novel fluorinated thieno[2,3-dlpyrimidine derivatives incorporating 1,3,4-thiadiazole were synthesized by a ......
基于砌块法在合成含氟杂环化合物中的重要性，介绍了近年来涉及利用三氟甲基作为合氟砌块合成含氟杂环化合物的研究进展。认为“一锅......
报道了4类含有CF2O桥键新型含氟化合物合成路线及制备方法 ,这4类化合物都没有出现液晶相,但都具有高的介电各向异性、低黏度,可以......
合成了标题化合物（C8H5F3N2S），通过元素分析和X-射线单晶衍射对其结构进行了表征。化合物的分子式是C8H5F3N2S，晶体属于单斜晶系，空间群......
以三氟苯乙酮、溴代烃和异氰酸酯为原料，在金属锌的促进下，室温条件下通过三组分“一锅法”反应合成了新型的含三氟甲基氨基甲酸酯类......
以4-三氟甲基苯甲醛和4-硝基苯乙酮为主要原料,设计经两步反应合成了一种含吡啶结构和三氟甲基侧基的芳香二胺———4-(4-三氟甲基......
目的合成三氟甲基取代单羰基姜黄素类似物,并考察其对人肺癌细胞A549和NCI-H460增殖的影响。方法以邻三氟甲基苯甲醛和酮(丙酮、环......
α,β-不饱和结构出现在许多重要药物合成中间体中,且α,β-不饱和醛及其衍生物的三氟甲基化产物在特定条件下可以水解生成具有活......
以３－三氟甲基－４－氨基－５－巯基－１，２，４－三唑（１）为原料，与芳醛在冰醋酸中缩合得相应Ｓｃｈｉｆｆ碱（２～５），（２～５）与各种仲胺和芳胺在室温下反应，制得２４个新的Ｍａｎｎｉｃｈ碱（６～９），利用ＩＲ，＾１ＨＮＭＲ、ＭＳ和元素分析确定了这......
为了发掘具有良好除草活性的新型化合物，以6-三氟甲基-1-取代脲嘧啶为原料，在无水碳酸钾条件下，N，N-甲基甲酰胺为溶剂，使用硫酸二甲酯进......
以6-氯嘌呤衍生物和6-溴嘌呤衍生物为原料，通过卤素交换反应制得6-氟嘌呤衍生物；通过烷氧基化反应制得6-三氟乙氧基嘌呤衍生物，通过三......
The importance of CF3-containing molecules in pharmaceuticals, agrochemicals and materials intrigues the intense interes......
Syntheses, Crystal Structures, and Antitumor Activities of Two 2-Trifluoromethyl-5,6,7,8-tetrahydrob
Two novel 2-trifluoromethyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine derivatives were synthesized by n......
