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本文报告707例精子自身抗体的研究结果。其中健康男性输精管绝育者278例,未绝育者231例;男性冠心病人输精管绝育者87例,未绝育者111例。明胶凝集试验(GAT)、试管玻片凝集试验(TSAT)和精子制动试验(SIT)检测结果表明:精子抗体在手术后6月内就已产生,并持续20年以上。曾作输精管绝育术的健康男性和冠心病人二组比较,抗体的阳性率和滴度皆无差异显著性。没有证据表明输精管绝育术后的精子免疫反应会增加冠心病的发病率。
This article reports the results of 707 cases of sperm autoantibodies. Among them, 278 cases of healthy male vas deferens and 231 cases of unvaccinated people were enrolled in this study. There were 87 cases of vas deferens in coronary heart disease in men and 111 cases of non-sterility. Gelatin agglutination test (GAT), test tube slide agglutination test (TSAT) and sperm brake test (SIT) test results show that: sperm antibodies have been produced within 6 months after surgery and lasted more than 20 years. There was no significant difference in antibody positive rate and titer between healthy men who had been in vasectomy and coronary heart disease patients. There is no evidence that sperm immune responses after vasectomy increase the incidence of coronary heart disease.