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首次报道了柔弱短指软珊瑚SinulariatenellaLi的 3个主要的西松烯二萜内酯 :dihydroflexibilide ( 1 ) ,flexibilide ( 2 )和sinulariolide ( 3 )的分离和体外抗肿瘤活性。这 3个化合物都显示出较强的抗肿瘤活性。
The isolation and in vitro anti-tumor activity of dihydroflexibilide (1), flexibilide (2) and sinulariolide (3) were reported for the first time for the three major coconpin lactone of SinulariatenellaLi, a soft-shelled soft coral. All three compounds showed strong anti-tumor activity.